… industrial toxicants can be assessed in vitro on excised human or animal skins. Numerous
… substance to mix with it and penetrate the dermis. With ethanol, a difference in flux between …

… It is assumed that the difference between the applied dose … highly toxic chemicals to be tested,
but just like any other method… assay for pesticide risk assessment. The workshop identified …

… We trace the evaluation of the early innovations of Burch and … coefficient compared to animal
and human skin models, the … had close to a 20-fold difference between in vitro and in vivo …

… is a good animal model to predict potential percutaneous … That for cadmium is a more
reasonable 3-fold difference. … but does not prevent penetration of water and other molecules. This …

… , protecting the body from toxic substances and pathogens. … animal skin models provide,
many different animal models … affect percutaneous absorption and permeation), hairless rat …

… Thus, evaluation of percutaneous penetration of the drug … compartment between which the
animal model membrane is … activity or other factors, such as perfusion differences. Thus, it …

… to toxic substances in the soil, air, or via handled chemicals that … , no study utilized animal
models to show how differences in … [22] reported that percutaneous penetration was increased …

… Another inconsistency between articles includes use of … Several factors that might affect
percutaneous penetration, and … solutions, animal models, washing techniques and analysis of …

… to obtain the percutaneous penetration parameters of OPEs; to … -activity relationship (QSAR)
model; to determine the levels and … Differences in OPEs concentrations among different toy …

… of toxic substances in the environment have a capacity to … We can only develop animal
models with the highest possible … dog as an animal model for percutaneous absorption. However…